About INFUSE® Bone Graft
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INFUSE® Bone Graft contains a manufactured bone graft material that is FDA-approved for use in certain oral surgery procedures, including sinus augmentation and localized alveolar ridge augmentation.
INFUSE® Bone Graft contains a synthetic (manufactured) bone graft material that has been approved by the U.S. Food and Drug Administration for use in certain oral and maxillofacial bone grafting procedures, including sinus augmentation and localized alveolar ridge augmentation.
INFUSE® Bone Graft consists of two main components: a manufactured version of a protein that's normally found in the body and a natural carrier for delivery of the protein. The protein is rhBMP-2 (recombinant human bone morphogenetic protein 2) in a pure, freeze-dried powder form. This is a naturally occurring protein common to all humans and animals with bone that is found in very small amounts, and its purpose is to stimulate bone formation at the site in which it's placed.
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The natural carrier is an absorbable collagen sponge (ACS), which is made from a material found in bone and tendons. The ACS releases the protein over time in the location where it is placed, and provides a scaffold on which new bone can grow. As the graft site heals, the ACS is absorbed and replaced by bone.
What Are The Benefits of INFUSE® Bone Graft?
One of the primary advantages of INFUSE® Bone Graft is that it is an alternative to autograft – the use of autogenous bone (from the hip, rib, leg, jaw or chin) for implantation into a void or defect elsewhere in the body, such as the bones of the jaw.
Prior to INFUSE® Bone Graft, autogeneous bone traditionally provided patients with the best grafting results in oral surgeries such as a sinus augmentation. INFUSE® Bone Graft eliminates the need for the bone-harvest surgery that autograft requires, an additional procedure that, depending on the location, may be painful for some patients and lengthen the overall healing process.
INFUSE® Bone Graft:
- Provides proven, predictable bone formation.
- Offers safety benefits by eliminating the need for bone to be harvested from the patient.
- Is supported by extensive research and clinical results.
- Has an active ingredient called rhBMP-2, a manufactured version of a protein found naturally in the body, and offers the potential for both bone growth and improved patient healing.
INFUSE® Bone Graft's unique mechanism of action promotes new bone formation:
- The application of INFUSE® Bone Graft results in the induction of normal bone at the site of implantation.
- The process includes the attraction of the patient's own bone-generating cells into the site.
- The bone induced by INFUSE® Bone Graft is normal physiologic bone.
How Is INFUSE® Bone Graft Used?
During your procedure, the rhBMP-2 protein, which is in powder form, is mixed with sterile water. The solution is then soaked into the ACS. Your surgeon will then place the protein-soaked ACS into the space he or she has prepared and then follow the normal surgical care protocol for your procedure.
The specific details of your particular oral surgery will vary, depending on the condition to be treated. Please discuss your treatment plan and the use of INFUSE® Bone Graft thoroughly with your oral surgeon.
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